Case Report

Invasive Micropapillary Carcinoma of the Breast: A Case Report

  • Özgül Paşaoğlu
  • Funda Canaz
  • Evrim Çiftçi
  • Ercüment Pasaoğlu

Received Date: 01.03.2011 Accepted Date: 28.11.2011 Meandros Med Dent J 2012;13(1):39-41

Invasive micropapillary carcinoma of the breast is a rare subtype of invasive ductal carcinoma. It's clinical characteristics include a high rate of lymph node metastasis, vascular invasion, and poor prognosis. A 70-year-old postmenopausal woman presented with a lesion on the right breast that had been first noted by ultrasound examination. Physical examination revealed no palpable mass. An excisional biopsy was done, and the diagnosis was invasive micropapillary carcinoma. The patient underwent a right modified radical mastectomy with axillary dissection. Histologically, the tumor was composed of pseudopapillary structures in clear spaces lined by delicate strands of fibrocollagenous stroma. The pseudopapillary structures were devoid of fibrovascular cores. Estrogen receptor and progestrone receptor were positive in the tumor cells, C-erb-B2 and WT1 were negative. Tumor cells showed membranous and cytoplasmic expression of Ca125. In this case, we described a rare subtype of invasive ductal carcinoma and discussed the histopathological and immunohistochemical findings.

Keywords: Breast, invasive micropapillary carcinoma, immunohistochemical examination