Clinical Investigation

Fetal and Placental Anthropometry and Blood Glucose Levels in Women at Low Risk of Gestational Diabetes Mellitus

  • Ali Riza ODABASI
  • Hasan YÜKSEL
  • Samet KAFKAS
  • Selda Demircan SEZER
  • Zekeriya GÜNER
  • Minegül EBEN
  • Ergün ONUR

Meandros Med Dent J 2006;7(3):13-18

Aim: To compare fetoplacental anthropometric outcomes of gestational diabetes mellitus (GDM) in screening negative and positive women Material and Methods: By retrospective surveillance of 317 women who delivered in their 38th-40thweek ofgestation and who had undergone glucose challenge test (GCT) in their 24th-28th of gestation, the screen negative and positive women (GCT-1st hour ≥140 mg/dl) were assigned into four groups: The screen positive women all of whose OGTT values were normal (n=24), screen positive women who had only one abnormal value (n=16),women negative for GDM (n=263) and women with GDM (n=14). Only GDM group was given a diet therapy. We compared fetal and placental weight (FW, PW), ponderal index and fetoplacental ratio (FPR). We also investigated the correlations between all variables. Results: There was no significant difference in all variables between the groups. There was no correlation between FW and all other variables. There was a positive correlation between PW and BMI and all OGTT values except OGTT 2 hour value. The correlation between PW and weight gain and FPR and GTT-0.hour value was negative, whereas a positive correlation between FPR and weight gain was determined. Conclusion: In a special population with a low risk of GDM, “having a negative diagnostic test or impaired glucose tolerance” do not adversely affect fetoplacental anthropometric outcomes. The same results also exist for the GDM cases. It might be due to the fact that the study was conducted in a low risk group and the diet therapy was appropriate. However, care should be taken in pregnant women at high risk.

Keywords: glucose screening in pregnancy, gestational diabetes mellitus, fetal weight, placental weight, fetoplacental ratio